Publications - MIACYC Project
2024
- Yeast Platforms for Production and Screening of Bioactive Derivatives of Rauwolscine
- A GAME changer in steroidal metabolite biosynthesis
- Genome-based discovery of pachysiphine synthases in Tabernaemontana elegans
- The Madagascar palm genome provides new insights on the evolution of Apocynaceae specialized metabolism.
- Emerging trends in plant natural products biosynthesis: a chemical perspective
- Structural diversity and chemical logic underlying the assembly of monoterpene indole alkaloids oligomers
- A chromosome-scale genome assembly of Rauvolfia tetraphylla facilitates identification of the complete ajmaline biosynthetic pathway
- SPOTLIGHT: Alpha carbonic anhydrases join the club of alkaloid biosynthetic enzymes
- Emerging trends in production of plant natural products and new-to-nature biopharmaceuticals in yeast.
- Combination of Machine Learning and Empirical Computation for the Structural Validation of Trirosaline, a Natural Trimeric Monoterpene Indole Alkaloid from Catharanthus roseus
2023
- Structure elucidation of an aspidofractinine-type monoterpene indole alkaloid from Melodinus reticulatus
- The Rauvolfia tetraphylla genome suggests multiple distinct biosynthetic routes for yohimbane monoterpene indole alkaloids in monoterpene indole alkaloid synthesis
- Unifying the configuration of historical alkaloids from Borreria capitata through an extensive spectroscopic reinvestigation.
- From the Spectroscopic Reassessment of Authentic Alkaloid Samples to the Molecular Networking-Guided Discovery of Criophylline-Related Analogues from Callichilia inaequalis
- Gaining access to acetyl-CoA by peroxisomal surface display.
- Medicinal plants enter the single-cell multi-omics era
- Biosynthesis of natural and halogenated plant monoterpene indole alkaloids in yeast
- Artificial intelligence for natural product drug discovery
- On the structures of the penduflorines from Tabernaemontana penduliflora
2022
- Pyrrovobasine, hybrid alkylated pyrraline monoterpene indole alkaloid pseudodimer discovered using a combination of mass spectral and NMR-based machine learning annotations.
- Emerging mechanistic insights into the regulation of specialized metabolism in plants
- Boosting lignan-precursor synthesis in yeast cell factories through co-factor supply optimization
- Genome Assembly of the Medicinal Plant Voacanga thouarsii
- A new path for terpenoid biosynthesis
- Towards a Better Understanding of Toxin Biosynthesis in Seaweeds
- More than a Catharanthus plant: A multicellular and pluri-organelle alkaloid-producing factory
- Computer-Assisted Design of Sustainable Syntheses of Pharmaceuticals and Agrochemicals from Industrial Wastes
- The Vinca minor genome highlights conserved evolutionary traits in monoterpene indole alkaloid synthesis
- Chromosome-scale genomes throw light on plant drug biosynthesis
- Identification of a second 16-hydroxytabersonine-O-methyltransferase suggests an evolutionary relationship between alkaloid and flavonoid metabolisms in Catharanthus roseus
- Social amoebae as a new chassis for drug production
2021
- Reappraisal of the Structure of Lyaline as the First Naturally Occurring Nacycline Monoterpene Indole Alkaloid.
- Structure Reassignment of Melonine and Quantum-Chemical Calculations-Based Assessment of Biosynthetic Scenari
- Computational biotechnology guides elucidation of the biosynthesis of the plant anticancer drug camptothecin
- Advances in decomposing complex metabolite mixtures using substructure- and network-based computational metabolomics approaches
- Plant to insect horizontal gene transfer: empowering whiteflies
- Peroxisome : a new hub for metabolic engineering in yeast
- Marine drugs: Biology, pipelines, current and future prospects for production
- Yeasts as Biopharmaceutical Production Platforms
MIACYC
a collaborative research project
"CE43 Bioéconomie, chimie, biotechnologie, procédés et approches système, de la biomasse aux usages"
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