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Chromosome-scale genomes throw light on plant drug biosynthesis

  • Pharmacie,
  • Santé-Sciences-Technologie,
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Date(s)

du 14 février 2022 au 30 septembre 2024

Lieu(x)

Site Grandmont

EA2106 BBV - Biomolécules et Biotechnologies végétales

Recent chromosome-scale genomes from prominent medicinal plants have provided unprecedent insight into the architecture and evolution of some prominent metabolic pathways. A story related in our new paper published in Trends in Pharmacological Sciences!

"Chromosome-scale genomes throw light on plant drug biosynthesis"   by Emily Amor Stander1,4, Thomas Dugé de Bernonville2'4, Nicolas Papon3 and Vincent Courdavault1*
Trends in Pharmacological Sciences 2022 : https://doi.org/10.1016/j.tips.2022.01.007

1Université de Tours, EA2106 Biomolécules et Biotechnologies Végétales, Tours, France
2Limagrain, Centre de Recherche, Route d'Ennezat, Chappes, France
3Univ. Angers, Univ. Brest, GEIHP, IRF, SFR ICAT, F-49000 Angers, France

 

Abstract

Recent chromosome-scale genomes from prominent medicinal plants have provided unprecedented insight into the architecture and evolution of some prominent metabolic pathways. These new technologies also facilitate the identification of plant drug biosynthetic genes and would likely accelerate the development of new bioengineering procedures to secure the supply of important plant-derived pharmaceuticals.

Keywords

specialized metabolites, gene identification, chromosome-scale genome,metabolic gene cluster, synteny