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On the structures of the penduflorines from Tabernaemontana penduliflora Author links open overlay panel

  • Santé-Sciences-Technologie,
Date(s)

du 15 avril 2023 au 31 mars 2026

Lieu(x)
BioCIS - Université Paris Saclay

In this article, Dr Mehdi Beniddir from the ANR project MIACYC and collaborators revised the structures of penduflorines from Tabernaemontana penduliflora

On the structures of the penduflorines from Tabernaemontana penduliflora

Beniddir MA, Göransson U, Robertson LP. On the structures of the penduflorines from Tabernaemontana penduliflora. Fitoterapia. 2023 Jun;167:105506. doi: 10.1016/j.fitote.2023.105506.

Abstract :

The structures of the recently published monoterpene indole alkaloids penduflorines A and B (1a and 1b), isolated from Tabernaemontana penduliflora (Apocynaceae), have been revised. Rather than an inseparable mixture of two compounds, they appear to be the known alkaloid vobasine (2). Although we could not comprehensively revise the structures of penduflorines C-E due to lacking spectral data, since their structural elucidations were based on that of 1a and 1b, their structures should also be treated with caution.

Keywords: Alkaloid; Apocynaceae; Monoterpene indole alkaloid; Structure revision; Vobasine.